Temporal patterns of synchrony in a pyramidal-interneuron gamma (PING) network

Synchronization in neural systems plays an important role many brain functions. the gamma frequency band (30–100 Hz) is involved a variety of cognitive phenomena; abnormalities synchronization are found schizophrenia and autism spectrum disorder. Frequently, strength not high, intermittent even on short time scales (few cycles oscillations). That is, network exhibits intervals followed by desynchronization. Neural circuit dynamics may show different distributions desynchronization durations if fixed. We use conductance-based exhibiting pyramidal-interneuron rhythm to study temporal patterning synchronized oscillations. that changes synaptic (as well as membrane kinetics) can alter synchrony. Moreover, we pattern synchrony be independent average strength. Even though vary, there tendency for with (although potentially numerous) desynchronizations, similar what was observed experimental studies brain. Recent suggested desynchronizations facilitate formation breakup transient assemblies. Thus, results this suggest make networks more efficient assemblies facilitation phenomena.